- Pac-Man Museum
- Peggle
- Perfect Dark
- Perfect Dark Zero
- Phantasy Star II
- Phantom Breaker: Battle Grounds
- Pinball FX
- Plants vs. Zombies
- Portal: Still Alive
- Portal 2
- Prince of Persia
- Putty Squad
- Puzzle Quest (added October 13, 2016)
- Puzzle Quest 2
- Puzzle Quest: Galactrix
- QIX++ Puzzlegeddon
- Rage
- Rayman 3 HD
- Rayman Origins
- Red Dead Redemption
- Red Faction: Battlegrounds
- R-Type Dimensions
- Runner 2
- Sacred 3
- Sacred Citadel
- Saints Row IV
- Sam & Max: Beyond Time & Space
- Sam & Max Save the World
- Samurai Shodown II
- Sega Vintage Collection: Alex Kidd & Co.
- Sega Vintage Collection: Monster World
- Sega Vintage Collection: Streets of Rage
- Shadow Complex
- Shank 2
- Shred Nebula
- Silent Hill: Downpour
- Skullgirls
- Small Arms
- Sonic & All-Stars Racing Transformed
- Sonic & Knuckles
- Sonic CD
- Sonic The Fighters
- Sonic The Hedgehog
- Sonic The Hedgehog 2
- Sonic The Hedgehog 3
- Sonic The Hedgehog 4: Episode 1
- Sonic The Hedgehog 4: Episode II
- Soulcalibur
- Soulcalibur II
- South Park: The Stick of Truth
- Space Giraffe
- Spelunky
- Splosion Man
- SSX
- Star Wars: The Force Unleashed
- Star Wars: The Force Unleashed II
- Super Meat Boy
- Supreme Commander 2
- Syberia
- Tekken Tag Tournament 2
